Journal: Bioactive Materials
Article Title: A sandwich-like nanofibrous scaffold with macrophage phenotype transformation and myogenic differentiation for skeletal muscle regeneration
doi: 10.1016/j.bioactmat.2025.05.008
Figure Lengend Snippet: Effect of gelatin content on the properties of PCL/Gelatin fibrous scaffolds. A) Representative SEM images, B) FFT images, and C) fiber orientation distribution of PCL, P7G3, P5G5, and P3G7 scaffolds. D) Tensile strength of scaffold with different gelatin content (n = 4; ∗∗∗ p < 0.001). E) Raman spectra of PCL, Gelatin, and P7G3. The red and green arrows indicate the characteristic peaks of PCL and gelatin at 1106 cm −1 and 1664 cm −1 , respectively. F) Laser-micro confocal Raman mapping of P7G3. G) Water contact angle and H) corresponding quantitative analysis of PCL, P7G3, P5G5, and P3G7 scaffolds (n = 3; ∗∗ p < 0.01, ∗∗∗ p < 0.001). I) The SEM images of PCL, P7G3, P5G5, and P3G7 fibrous scaffolds after degradation for 14 days. J) The residual mass of PCL, P7G3, P5G5, and P3G7 fibrous scaffolds after degradation for different time.
Article Snippet: Laser micro-confocal Raman spectroscopy (LabRAM HR Evolution, HORIBA, Japan) was employed to observe the distribution of gelatin in the P7G3 fibers.
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